# What does duration of follow up mean?

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## How do you calculate follow-up duration?

Once you’ve chosen what period you are interested in, the answer is clear: the median is the length of “follow-up” such that half your subjects were followed up for less than this length of time, half were followed up for more.

## What are follow-up measures?

Follow-up measures were measures applied to marketing authorisations, setting out studies and other activities that the Agency and CHMP had asked the marketing-authorisation holder to perform. Marketing-authorisation holders affected by these changes will receive an outcome fax for each of their products as applicable.

## What is completeness of follow-up?

We propose a simple measure of completeness that is the ratio of the total observed persontime and the potential person-time of follow-up in a study. … Each person who does not have an event can be included in a survival analysis for the period up to the time at which they are censored.

## Why are follow-up periods important?

Post-trial follow-up of large RCTs is important, not only for defining the effect of an intervention long-term but also for ascertaining the safety profile and potential hazards which might not be apparent during the relatively brief in-trial period.

## How do I stop losing to follow up?

Since there is no way of predictiing the effects of loss to follow up, researchers do their best to reduce it by maintaining contact with participants at regular intervals, collecting contact information from friends or relatives that would know how to reach a participant should s/he move, using the National Death …

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## What is follow up in research?

A follow-up study occurs after research or a treatment has been presented to the participant or patient. It is used to ascertain if the effects of the treatment condition are still present in the participants.

## What is median follow-up time?

In statistics, median follow-up is the median time between a specified event and the time when data on outcomes are gathered. The concept is used in cancer survival analyses.

## What is acceptable loss to follow-up?

A good rule of thumb is that <5% loss leads to little bias, while >20% poses serious threats to validity. However, even less than 20% loss to follow-up can be a problem. Considering a worst-case scenario can help determine whether loss to follow-up poses a potential threat to validity.

## Why is follow-up important in clinical trials?

The completeness of follow-up is an important determinant of validity [5,6]. Clinical studies are expected implicitly to consider the course of all participants up to the “study end” [7]. … Therefore, studies should declare at least how complete their follow-up was, since otherwise their validity cannot be judged [13].