What was Griffith attempting to do when he discovered transformation?

What was Frederick Griffith trying to achieve in his transformation?

Frederick Griffith: Bacterial transformation. In 1928, British bacteriologist Frederick Griffith conducted a series of experiments using Streptococcus pneumoniae bacteria and mice. Griffith wasn’t trying to identify the genetic material, but rather, trying to develop a vaccine against pneumonia.

What was Griffith trying to discover when he found the transforming principle?

Griffith concluded that the heat-killed bacteria somehow converted live avirulent cells to virulent cells, and he called the component of the dead S-type bacteria the “transforming principle.”

What was the purpose of Griffith’s experiment?

Research question: The original purpose of Griffith’s experiment was to test whether or not the bacteria synthesized their own polysaccharide capsule. He eventually answered how non-capsulated strains of Pneumococcus bacteria became virulent by providing them with capsular material from another strain.

Why did Griffith call what he saw transformation?

Griffith called the process he observed transformation because the mouse had been transformed. the harmful bacteria had been transformed. the harmless bacteria had been transformed.

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What was Frederick Griffith trying to answer?

Frederick Griffith: Bacterial transformation. In 1928, British bacteriologist Frederick Griffith conducted a series of experiments using Streptococcus pneumoniae bacteria and mice. Griffith wasn’t trying to identify the genetic material, but rather, trying to develop a vaccine against pneumonia.

What did Frederick Griffith do?

Frederick Griffith, (born October 3, 1877, Eccleston, Lancashire, England—died 1941, London), British bacteriologist whose 1928 experiment with bacterium was the first to reveal the “transforming principle,” which led to the discovery that DNA acts as the carrier of genetic information.

What did Griffith discover quizlet?

How did Griffith’s experiment help demonstrate that DNA is the carrier of genetic info? It found that the heritable factor is heat stable, so it could not be proteins. What did Griffith do in his experiment? He injected mice with two strains of Streptococcus pneumoniae, which causes pneumonia in the mice.

What evidence from Griffith’s investigation suggested that there was a transforming principle?

What evidence suggested that there was a transforming principle? When the mice died and Griffith found live S bacteria in blood samples from the dead mice! Griffith concluded that some material must have been transferred from the heat-killed S bacteria to the live R bacteria.

How did he prove that some transforming principle is responsible for transformation of the non virulent strains of bacteria into the virulent form?

Griffith had discovered that he could convert the R strain into the virulent S strain. After he injected mice with R strain cells and, simultaneously, with heat-killed cells of the S strain, the mice developed pneumonia and died. … The S strain extract somehow had “transformed” the R strain bacteria to S form.

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What was the hypothesis of Griffith’s experiment?

Based on these observations, Griffith hypothesized that a chemical component from the virulent S cells had somehow transformed the R cells into the more virulent S form (Griffith, 1928).

What was the conclusion of Griffith’s experiment?

Conclusion: Based on the observation, Griffith concluded that R strain bacteria had been transformed by S strain bacteria. The R strain inherited some ‘transforming principle’ from the heat-killed S strain bacteria which made them virulent. And he assumed this transforming principle as genetic material.

What is a possible hypothesis for Frederick Griffith’s experiment?

What was Griffith’s hypothesis based on transformation? when live, harmless bacteria and heat-killed bacteria are mixed, some factor was transferred from the heat-killed cells into the live cells. That factor must contain information that could change harmless bacteria into disease-causing ones.